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In addition to our screening and profiling services, DiscoveRx also offers a unique method in which to deorphanize GPCRs. As a universal G protein-independent assay that generates a receptor specific signal, the PathHunter ß-Arrestin platform is ideal for de-orphanization campaigns. Our Orphan Receptor Panel has been successfully used for the identification of novel ligand and receptor pairings. With 76 ready-to-assay oGPCR cell lines, we can deliver full panel screening data in less than 4 weeks.
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