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DiscoveRx offers the largest collection of validated GPCR functional assays for screening and profiling. Our PathHunter™ ß-Arrestin technology is a direct, universal platform for measuring compound action independent of G-protein signaling through ß-Arrestin recruitment to the GPCR. We also offer second messenger detection of cAMP and calcium mobilization in naturally coupled systems. Utilizing multiple approaches can provide valuable information in a high biological context and lead to novel drug discovery.
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